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Research

Pulmonary delivery of virosome-bound antigen enhances antigen-specific CD4+ T cell proliferation compared to liposome-bound or soluble antigen

Pulmonary administration of biomimetic nanoparticles loaded with antigen may represent an effective strategy to directly modulate adaptive immune responses

Research

‘Is it like one of those infectious kind of things?’ The importance of educating young people about HPV and HPV vaccination at school

Greater knowledge and understanding of National Human Papillomavirus vaccination appeared to promote positive attitudes towards vaccination

Research

Genotype and phenotype spectrum of NRAS germline variants

Here we describe 19 new cases with RASopathy due to disease-causing variants in NRAS

Research

Somatosensory discrimination intervention improves body position sense and motor performance in children with hemiplegic cerebral palsy

The intervention group improved in goal performance, proprioception, and bimanual hand use and maintained improvement at 6-mo follow-up.

Research

Long-term outcomes from acute rheumatic fever and rheumatic heart disease: A Data-Linkage and Survival Analysis Approach

Adverse outcomes for people with acute rheumatic fever and rheumatic heart disease and the effect of comorbidities and demographic factors on these outcomes

Research

Autism Spectrum Disorder, Language Disorder, and Social (Pragmatic) Communication Disorder: Overlaps, Distinguishing Features, and Clinical Implications

Strictly defined cases of social (pragmatic) communication disorder and specific language impairment can be distinguished from autism spectrum disorder

Research

A genome-wide approach to children's aggressive behavior: The EAGLE consortium

Common variants at 2p12 show suggestive evidence for association with childhood aggression

Research

Early Nutrition as a Major Determinant of 'Immune Health': Implications for Allergy, Obesity and Other Noncommunicable Diseases

A better understanding of nutritional programming of immune health may lead to dietary strategies that reduce the burden of many inflammatory diseases

Research

Effects of maltreatment and parental schizophrenia spectrum disorders on early childhood social-emotional functioning: a population record linkage study

Childhood maltreatment and history of parental SSD are associated independently with poor early childhood social-emotional functioning