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novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunctionThis study thus identified a novel small molecule that rapidly kills MLL-rearranged leukemia cells by targeting a metabolic vulnerability
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B Part of It School Leaver protocol: an observational study to assess the impact of a meningococcal serogroup B vaccine programme on carriage of Neisseria meningitidisThis study will assess the impact of MenB vaccine (4CMenB) on carriage prevalence in school leavers in South Australia
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Differential SLC6A4 methylation: a predictive epigenetic marker of adiposity from birth to adulthoodThese data suggest that altered methylation of CpG loci within SLC6A4 may provide a robust marker of adiposity across the life course
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Gender-affirming hormones and surgery in transgender children and adolescentsThis Review explores the available published evidence on gender-affirming cross-sex hormone and surgical interventions in transgender children
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Prenatal maternal stress events and phenotypic outcomes in Autism Spectrum DisorderASD, in the context of prenatal maternal stress exposure, may be associated with a more severe phenotype, particularly when there are multiple prenatal exposures
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Record linkage study of the pathogen-specific burden of respiratory viruses in childrenReliance on hospital discharge diagnosis codes alone will likely underestimate the burden of respiratory viruses
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Psychiatric disorders during early adulthood in those with childhood onset type 1 diabetes: Rates and clinical risk factors from population-based follow-upTo determine the incidence of and risk factors for psychiatric disorders in early adulthood in patients with childhood onset type 1 diabetes (T1D)
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Bugging allergy; role of pre-, pro- and synbiotics in allergy preventionHere, we summarize and discuss findings of randomized clinical trials that have examined the effects of these strategies on short and long-term.
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Differences in serum zinc levels in acutely ill and remitted adolescents and young adults with bulimia nervosa in comparison with healthy controls – a cross-sectional pilot studyResearch has implicated that changes in Zn metabolism may be associated with the biological underpinnings of eating disorders, in particular anorexia nervosa.
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Severe hypoglycemia rates are not associated with HbA1c: A cross-sectional analysis of 3 contemporary pediatric diabetes registry databasesTo examine the association between glycated hemoglobin (HbA1c) and severe hypoglycemia rates in patients with type 1 diabetes receiving usual care.