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Jet versus vibrating mesh nebulizer for tobramycin aerosol in spontaneously breathing children with tracheostomies: A simulation studyTracheostomy tubes act as foreign bodies, predisposing the surrounding airway to respiratory infections. Initial treatment for infections is topical - nebulized tobramycin - although guidelines for standardized treatment are lacking.
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Artemisinin combination therapy at delivery to prevent postpartum malaria: A randomised open-label controlled trialAlthough the incidence of malaria is increased in women in endemic areas after delivery compared to non-pregnant women, no studies have assessed the benefit of presumptive antimalarial treatment given postpartum.
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VEGF-D promotes pulmonary oedema in hyperoxic acute lung injuryOur studies show that Vegf-d promotes oedema in response to hyperoxia in mice and support the hypothesis that VEGF-D signalling promotes vascular leak in human HALI.
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Pooled Analysis of Physical Activity, Sedentary Behavior, and Sleep among Children from 33 CountriesThe prevalence estimates of physical activity, sedentary behavior, and sleep (collectively known as movement behaviors) in 3- and 4-year-old children worldwide remains uncertain.
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New South Wales child development study (NSW-CDS): An Australian multiagency, multigenerational, longitudinal record linkage studyIdentify risk and protective factors for later childhood-onset and adolescent-onset mental health problems, and other adverse social outcomes
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Phage therapy to treat cystic fibrosis Burkholderia cepacia complex lung infections: perspectives and challengesgeBurkholderia cepacia complex is a cause of serious lung infections in people with cystic fibrosis, exhibiting extremely high levels of antimicrobial resistance. These infections are difficult to treat and are associated with high morbidity and mortality.
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Increasing incidence of type 2 diabetes in Indigenous and non-Indigenous children in Western Australia, 1990-2012In this study, we aimed to determine the incidence and incidence rate trends of childhood T2D in Indigenous and non-Indigenous children in WA.
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Centralising Local Aboriginal Language and Culture in Healthy Skin Books on the See Treat Prevent (SToP) Trial in the Kimberley Region of Western Australia: A Process and Impact InquiryLanguage is significant for communicating knowledge across cultures and generations and has the power to attribute meanings and alter our worldviews.
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Good-quality diet in the early years may have a positive effect on academic achievementQuality of early diet may be a predictor for later academic achievement
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Systematic review of the evidence for treatment and management of common skin conditions in resource-limited settings: An updateThe skin is the largest and most visible organ of the human body. As such, skin infections can have a significant impact on overall health, social wellbeing and self-image.
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Early life events and motor development in childhood and adolescence: A longitudinal studyAntenatal, perinatal and neonatal factors affecting motor development from late childhood to adolescence were explored.
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Exposure to biodiesel exhaust is less harmful than exposure to mineral diesel exhaust on blood-brain barrier integrity in a murine modelEmerging data suggest that air pollution is a persistent source of neuroinflammation, reactive oxygen species, and neuropathology that contributes to central nervous system disorders. Previous research using animal models has shown that exposure to diesel exhaust causes considerable disruption of the blood-brain barrier, leading to marked neuroinflammation.
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Using online environments to build school staff capacity to address student wellbeingTeachers and school executive teams are often required to address health and wellbeing issues affecting students' learning
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Novel approaches to measuring cognition in individuals with severe to profound functional impairment: A pilot study in SCN2A-related disorderValid clinical outcome assessments with the ability to capture meaningful aspects of neurodevelopment for individuals with neurogenetic conditions associated with profound functional impairments are lacking, yet critical for clinical care and clinical trial readiness.
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A prospective investigation of dietary patterns and internalizing and externalizing mental health problems in adolescentsOur findings only lend partial support to a link between diet and mental health, specific to females consuming a Western diet and to externalizing behaviours
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Antibodies in breast milk: Pro-bodies designed for healthy newborn developmentThis manuscript sheds light on the impact of maternal breast milk antibodies on infant health. Milk antibodies prepare and protect the newborn against environmental exposure, guide and regulate the offspring's immune system, and promote transgenerational adaptation of the immune system to its environment.
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Effect of exercise intensity on glucose requirements to maintain euglycemia during exercise in type 1 diabetesInverted-U relationship between exercise intensity and glucose requirement
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Short-term outcomes in infants following general anesthesia with low-dose sevoflurane/dexmedetomidine/remifentanil versus standard dose sevoflurane (The TREX trial)The Trial Remifentanil DEXmedetomidine trial aimed to determine if, in children < 2 years old, low-dose sevoflurane/dexmedetomidine/remifentanil anesthesia is superior to standard dose sevoflurane anesthesia in terms of global cognitive function at 3 years of age.
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Brief Report: Burden of Care in Mothers of Children with Autism Spectrum Disorder or Intellectual DisabilityMothers of children with autism spectrum disorder or intellectual disability have higher rates of treatment episodes for psychiatric disorders