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Research
Recurrent MET fusion genes represent a drug target in pediatric glioblastomaWe identified previously unidentified gene fusions involving the MET oncogene in pediatric glioblastoma
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A fine balance and a shared learning journey: Exploring healthcare engagement through the experiences of youth with Neuromuscular DisordersExplored Youth with Neuromuscular Disorders perceptions of health, health behaviors and healthcare engagement
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Immunodominant T-cell epitopes in the VP1 capsid protein of rhinovirus species A and COur results indicate a dissociation between the antibody and T-cell responses to rhinoviruses
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Developmental trajectories of sleep problems from childhood to adolescence both predict and are predicted by emotional and behavioral problemsFindings from this study provide empirical evidence for the heterogeneity of sleep problems and their development
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Severe winter asthma exacerbations can be prevented by omalizumab, but there is no carryover effect.Recurrent severe asthma exacerbations are associated with decreased lung growth or accelerated loss of long function and add substantially to cost and morbidity
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Sun exposure and its effects on human health: Mechanisms through which sun exposure could reduce the risk of developing obesity and cardiometabolic dysfunctionThe cardiometabolic protective effects of ultraviolet radiation and mechanistic pathways through which ultraviolet radiation could be beneficial.
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Vitamin D and allergic airway disease shape the murine lung microbiome in a sex-specific mannerMaintaining sufficient vitamin D is necessary for optimal lung health, and vitamin D may modulate the lung microbiome in a sex-specific fashion
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Reduced transforming growth factor β1 (TGF-β1) in the repair of airway epithelial cells of children with asthmaEvidence into the role of TGF-β1 in airway epithelial repair in asthma is still controversial. This study tested the hypothesis that the reduced TGF-β1 levels previously observed in paediatric asthmatic airway epithelial cells directly contribute to the dysregulated repair seen in these cells.
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Epidural insertion height for ureteric reimplant surgery; does location matter?The caudal catheter technique was superior at reducing pain interventions, particularly bladder spasm interventions
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Sole-parent work schedules and adolescent wellbeing: Evidence from AustraliaExplores the effects of parental work schedules on the mental and physical health of adolescents aged 15-20 in sole-parent families