Projects
Research
Developmental-associated dysregulation of innate anti-microbial immunity in early life as a determinant of susceptibility to atopic asthmaOne of the strongest risk factors for asthma is having chest infections during infancy that are so severe that they trigger symptoms of fever & wheeze
Research
The role of bacterial infections during infancy in asthma developmentIn this project we are studying how interactions between bacteria and viruses in children's airways promote the development of allergy and asthma.
Research
Studies on the immunological mechanisms underlying progression versus resolution of asthma between adolescence and adulthoodThis project seeks new information on asthma disease mechanisms, to help propel development of new and better anti-asthma drugs.
Research
Epigenetic changes underpinning allergen sensitization: a twin-based studyWe are studying immune cells from identical twins of which one suffers and one does not suffer from allergic disease to identify specific mechanisms that may pl
Research
Characterization of “bystander” effects of the diphtheria-pertussis-tetanus (DTP) vaccine on the IgE systemWe are seeking more detailed information on how the immune system of infants responds to the vaccine, with the aim of identifying which aspects of the immune r