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Research
A modular approach to forecasting COVID-19 hospital bed occupancyMonitoring the number of COVID-19 patients in hospital beds was a critical component of Australia's real-time surveillance strategy for the disease. From 2021 to 2023, we produced short-term forecasts of bed occupancy to support public health decision-making.
Research
Rewiring endogenous genes in CAR T cells for tumour-restricted payload deliveryThe efficacy of chimeric antigen receptor (CAR) T cell therapy in solid tumours is limited by immunosuppression and antigen heterogeneity. To overcome these barriers, 'armoured' CAR T cells, which secrete proinflammatory cytokines, have been developed. However, their clinical application has been limited because of toxicity related to peripheral expression of the armouring transgene.
Research
The mitophagy receptors BNIP3 and NIX mediate tight attachment and expansion of the isolation membrane to mitochondriaBNIP3 and NIX are the main receptors for mitophagy, but their mechanisms of action remain elusive. Here, we used correlative light EM (CLEM) and electron tomography to reveal the tight attachment of isolation membranes (IMs) to mitochondrial protrusions, often connected with ER via thin tubular and/or linear structures.
Children in the tiny Pacific nation of Tuvalu face a unique threat that should be a wake-up call to other countries across the world.
In 2020, the National Closing the Gap partnership made improving early development of Aboriginal and Torres Strait Islander children one of its top priorities. Australia will measure progress in this area using the AEDC.
Research
Gender DiversityNot all children or teenagers identify with the gender they were assigned at birth. As a result, some may choose to change their name, their clothes or their body. With considerably higher rates of depression, anxiety, self-harm and attempted suicide, the need for specialist mental health services has been recognised.
The Kids Research Institute Australia Government Relations Advisor Fiona Roche said the BEACHES project was a great example of how the Institute is increasingly working in partnership with Government
Lucia Wright is a happy, confident 16-year-old who loves her family, friends, drama, science and making the most of her newfound independence.
Strawberries, slime and sliced bread are being used as tools to educate and inspire the next generation of researchers, as part of the The Kids Discovery Centre Schools & Outreach Program.
Study found children aged 2–5 years from dog-owning households had increased pro-social behaviours like sharing and cooperating, when compared to children without a dog.