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Research

A modular approach to forecasting COVID-19 hospital bed occupancy

Monitoring the number of COVID-19 patients in hospital beds was a critical component of Australia's real-time surveillance strategy for the disease. From 2021 to 2023, we produced short-term forecasts of bed occupancy to support public health decision-making. 

Research

Rewiring endogenous genes in CAR T cells for tumour-restricted payload delivery

The efficacy of chimeric antigen receptor (CAR) T cell therapy in solid tumours is limited by immunosuppression and antigen heterogeneity. To overcome these barriers, 'armoured' CAR T cells, which secrete proinflammatory cytokines, have been developed. However, their clinical application has been limited because of toxicity related to peripheral expression of the armouring transgene. 

Research

The mitophagy receptors BNIP3 and NIX mediate tight attachment and expansion of the isolation membrane to mitochondria

BNIP3 and NIX are the main receptors for mitophagy, but their mechanisms of action remain elusive. Here, we used correlative light EM (CLEM) and electron tomography to reveal the tight attachment of isolation membranes (IMs) to mitochondrial protrusions, often connected with ER via thin tubular and/or linear structures.

Facing the future: Giving kids in Tuvalu a better start as their country sinks into the sea

Children in the tiny Pacific nation of Tuvalu face a unique threat that should be a wake-up call to other countries across the world.

Closing the Gap - Hitting ‘reset’ on how we measure early development in Aboriginal kids

In 2020, the National Closing the Gap partnership made improving early development of Aboriginal and Torres Strait Islander children one of its top priorities. Australia will measure progress in this area using the AEDC.

Research

Gender Diversity

Not all children or teenagers identify with the gender they were assigned at birth. As a result, some may choose to change their name, their clothes or their body. With considerably higher rates of depression, anxiety, self-harm and attempted suicide, the need for specialist mental health services has been recognised.

Partnering with government to influence policy and practice

The Kids Research Institute Australia Government Relations Advisor Fiona Roche said the BEACHES project was a great example of how the Institute is increasingly working in partnership with Government

New technology the Wright treatment for Lucia

Lucia Wright is a happy, confident 16-year-old who loves her family, friends, drama, science and making the most of her newfound independence.

Mess + fun = future STEM stars

Strawberries, slime and sliced bread are being used as tools to educate and inspire the next generation of researchers, as part of the The Kids Discovery Centre Schools & Outreach Program.

Dogs and kids - good for the head, heart and health

Study found children aged 2–5 years from dog-owning households had increased pro-social behaviours like sharing and cooperating, when compared to children without a dog.