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Research

Missed Opportunities for Diagnosing Acute Rheumatic Fever

We have read with interest the new publication by Rouhiainen and colleagues on missed opportunities for preventing or diagnosing acute rheumatic fever (ARF).

Research

Development and Validation of a Stability-Indicating RP-HPLC Method for Edaravone Quantification

Edaravone is used to treat motor neurone disease (MND) by slowing disease progression and prolonging survival time. Currently, it is available as an IV infusion (Radicava®, Jersey City, NJ, USA) and an oral liquid suspension (Radicava ORS®, Jersey City, NJ, USA). Development of novel edaravone formulations is still an active field of research that requires a validated stability-indicating assay capable of providing specific, precise, and accurate quantification of edaravone content. 

The immortal legacy of Jette Ford

The Institute farewelled one of its most treasured employees this year, as The Kids Cancer Centre research officer Jette Ford closed the door on a quietly stellar 37-year career which has helped to change the face of cancer research in WA and around the world.

Vaccine push cuts meningococcal cases

Ten years of dedicated research investigating the Meningococcal ACWY vaccine paid off 20 times over in 2019, after its inclusion on the National Immunisation Program saw a significant decrease in children being diagnosed with the deadly disease.

Leveraging global lung health expertise to help preterm bubs

The world’s leading preterm scientists and doctors have joined forces to help give babies born very prematurely, the best possible life.

Research supports an innovative suicide prevention program

A series of suicides among young people south of Perth in 2016 sparked a major overhaul of how support is offered to the people left behind after someone takes their own life.

Making tonsil surgery safer

World-first findings from the collaborative REACT study – a joint project between The Kids, PCH, UWA and Curtin University – have led to the asthma medication Ventolin being routinely given to paediatric patients before tonsillectomy surgery to prevent respiratory complications.

Staying acT1ve with type 1 diabetes

A ground-breaking new app developed by The Kids researchers may soon make exercising safer for young people with type 1 diabetes.

Finding the right recipe for youth mental health

In early 2021, The Kids Research Institute Australia researcher Dr Amy Finlay-Jones led a global team in trying to answer that question to help better prioritise mental health spending.

Research

Transmission potential of Streptococcus pyogenes during a controlled human infection trial of pharyngitis

Controlled human infection (CHI) models can provide insights into transmission of pathogens such as Streptococcus pyogenes (Strep A). As part of the Controlled Human Infection with Penicillin for Streptococcus pyogenes (CHIPS) trial, we explored the potential for transmission among participants deliberately infected with the Strep A emm75 strain.