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Airway epithelial cells act through multiple mechanisms to function as an important component of the pulmonary defence strategy that is crucial...
For 20 years, the hygiene hypothesis has dominated attempts to explain the increasing prevalence of allergic disease. A causal link between maternal innate immu
Epidemiologic associations between viral lower respiratory infections (LRIs) and asthma in later childhood are well known
There is increasing evidence that the functional state of the immune system at birth is predictive of the kinetics of immune maturation in early infancy.
Atopy and asthma are commonly initiated during early life, and there is increasing interest in the development of preventive treatments for at-risk children.
This chapter describes the preparation of respiratory tract tissue from both mice and rats for the isolation of respiratory tract dendritic cells (RTDC).
Anti-viral innate immune responses may be impaired in asthma, although the mechanisms are not well understood.
This study compared the potency and immunomodulatory effects of measles mumps rubella (MMR) vaccine given to infants alone or in combination with varicella...
Appropriate innate immune function is essential to limit pathogenesis and severity of severe lower respiratory infections (sLRI) during infancy, a leading cause of hospitalization and risk factor for subsequent asthma in this age group.
Researchers at The Kids Research Institute Australia have found children with vitamin D deficiency are more likely to develop asthma.