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Research
Vitamin D supplementation of initially vitamin D-deficient mice diminishes lung inflammation with limited effects on pulmonary epithelial integrityIn disease settings, vitamin D may be important for maintaining optimal lung epithelial integrity and suppressing inflammation, but less is known of its effects prior to disease onset.
Research
Developing an Online Tool to Promote Safe Sun Behaviors With Young Teenagers as Co-researchersDespite education about the risks of excessive sun exposure, teenagers in Australia are sun-seeking, with sunburn common in summer. Conversely, some regular (time-limited) exposure to sunlight (that avoids sunburn) is necessary for vitamin D and healthy bones and other molecules important for immune and metabolic health. New interventions are thus required to better support teenagers to make healthy and balanced decisions about their sun behaviors.
Research
Use of linked administrative and laboratory data to confirm that serum 25(OH)D levels in pregnant women can be predicted from satellite estimates of ultraviolet radiationSerum 25 hydroxyvitamin D [25(OH)D] levels of pregnant women have been linked to various health outcomes in their offspring. Satellite-derived ultraviolet radiation (UVR) data have been used as a proxy for 25(OH)D levels, as individual-level cohort studies are time-consuming, costly and only feasible for common outcomes.
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The challenges of developing and optimising an assay to measure 25-hydroxyvitamin D in salivaWe have developed an LC-MS/MS assay that accurately measures saliva 25(OH)D3 levels, which correlated with serum levels
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Characterising nitric oxide-mediated metabolic benefits of low-dose ultraviolet radiation in the mouse: a focus on brown adipose tissueNon-burning (low-dose) UVR suppresses the BAT 'whitening', steatotic and pro-diabetic effects of consuming a high-fat diet through skin release of nitric oxide
News & Events
UV offers new hope in fight against MSPeople at risk of developing multiple sclerosis (MS) have been offered a beacon of hope thanks to research into UV exposure.
News & Events
Vitamin D deficiency linked to childhood asthmaResearchers at The Kids Research Institute Australia have found children with vitamin D deficiency are more likely to develop asthma.
Research
Vitamin D metabolites are lower with active Crohn’s disease and spontaneously recover with development of remissionWe aimed to characterise vitamin D metabolism in a cohort of patients with active and inactive Crohn’s disease
Research
Epigenome-wide analysis links SMAD3 methylation at birth to asthma in children of asthmatic mothersWe sought to assess whether the trajectory to asthma begins already at birth and whether epigenetic mechanisms, contribute to asthma inception.
Research
Reticulon-1 and reduced migration toward chemoattractants by macrophages differentiated from the bone marrow of ultraviolet-irradiated and ultraviolet-chimeric miceBy using an anti-reticulon-1 Ab, a role for reticulon-1 in macrophage migration toward both CSF-1 and CCL2 was confirmed.