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Tuberculosis (TB) is caused by Mycobacterium tuberculosis (Mtb) and is a leading cause of death. BCG is the only licensed TB vaccine. Preclinical studies have shown that in adults, intravenous administration of BCG improves protection against TB. We hypothesize that intradermal administration of BCG to the human newborn leads to low-grade BCG bacteremia and that this systemic dissemination improves protection against Mtb infection. This hypothesis is based on supporting observations including animal and human studies. It is a testable hypothesis and offers to deliver immediately actionable insight to advance the global efforts against TB.
With cochlear implantation becoming increasingly performed worldwide, an understanding of the risk factors, preventive measures, and management of cochlear implant (CI) infection remains important given the significant morbidity and cost it conveys.
Leclercia adecarboxylata is a rare cause of septic arthritis in children, and has intrinsic resistance to common antibiotics. We describe two cases of L. adecarboxylata septic arthritis in children that required re-presentation to hospital with prolonged treatment, and highlight the importance of considering L. adecarboxylata as a potential cause of infection among children with penetrating injuries and associated environmental exposure.
Status epilepticus is associated with significant morbidity and mortality. While vaccine-proximate status epilepticus (VP-SE) has rarely been associated with cases of Dravet syndrome, it is not known whether VP-SE differs clinically from non-vaccine proximate status epilepticus (NVP-SE).
In this blog, Curtin University Occupational Therapy students Julia Walker and Mandy Bull delve into the history of Occupational Therapy in Australia.
Our researchers have been busy. Here's a look at some of their work to be published recently.
ENDIA (Environmental Determinants of Islet Autoimmunity) is a national observational study into the causes of Type 1 Diabetes in childhood.
It's the new school year and by now your child's school should have a copy of their updated Diabetes Management Plan. Adele Connor, Diabetes in
Diabetes-related news, funding announcements and our latest published research.
With a little over a week before outpatient clinics move from Princess Margaret Hospital (PMH) to Perth Children’s Hospital (PCH), now is the time to familiarise yourself with all the information you need to know before you make your first visit.