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The rates of RHD in Timor-Leste are among the highest in the world, and prevalence is higher among girls than boys

Rheumatic heart disease (RHD) after group A streptococcus (GAS) infections is heritable and prevalent in Indigenous populations. Molecular mimicry between human and GAS proteins triggers proinflammatory cardiac valve-reactive T cells.

We conducted a systematic review of clinical trials and observational studies that address the utility of SXT for SSTI treatment, caused by either GAS or MRSA

This study sought to determine relationships, by gender, between childhood behaviour problems and adolescent risky sexual behaviours and substance use.

Jonathan Carapetis AM AM MBBS FRACP FAFPHM PhD FAHMS Executive Director; Co-Head, Strep A Translation; Co-Founder of REACH 08 6319 1000 contact@

Indigenous Australians are much more likely to die from Rheumatic Heart Disease than other Australians.

We describe the initiation and summary outcomes of a public health system approach for complex undiagnosed patients- the Undiagnosed Diseases Program - WA

This review outlines a clinical development strategy detailing the phases of development required for registration of a candidate Group A streptococci vaccin

RHD is an important cause of disability and death in low- and middle-income countries.

Echocardiographic screening for rheumatic heart disease is cost-effective in our context