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Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013

We estimated age-sex-specific all-cause mortality using the GBD 2010 methods with some refinements to improve accuracy applied to an updated database of vital registration, survey, and census data.

Revision of the Jones Criteria for the Diagnosis of Acute Rheumatic Fever in the Era of Doppler Echocardiography: A Scientific Statement From the American Heart Association

The goal of this statement was to review the historic Jones criteria used to diagnose acute rheumatic fever in the context of the current epidemiology of the disease and to update those criteria to also take into account recent evidence supporting the use of Doppler echocardiography.

Rheumatic Fever: What is New?

Vaccines offer the ultimate solution to prevention and reduction of ARF rates; however, research is still at early stages.

The usability and feasibility of a self-compassion chatbot (COMPASS) for youth living with type 1 diabetes

Although it is well established that youth with type 1 Diabetes (T1D) experience high rates of distress, current clinical care is often under-resourced and unable to provide sufficient or timely psychological support. The current study was designed to evaluate the safety, usability and feasibility of 'COMPASS,' a self-compassion chatbot intervention. 

Ways of working in Aboriginal and Torres Strait Islander Community Controlled Health Organisations: describing a conceptual model of comprehensive primary healthcare characteristics

This research sought to describe a conceptual model of Aboriginal and Torres Strait Islander Community Controlled Health Organisation (ATSICCHO) primary health care, and the fundamental role ATSICCHOs exercise in addressing critical service gaps needed to achieve equitable outcomes for Aboriginal and Torres Strait Islander peoples.

The longitudinal network of social and emotional development in middle childhood

The understanding of children's social and emotional development in middle childhood is critical to promote well-being throughout the life course. Children who fail to develop social and emotional competencies are more likely to experience difficulties in adulthood and, in the worst case, psychopathology. The current study will employ Cross-Lagged Network Models to investigate children's social and emotional development among Australian children aged 6 to 10 years. 

Sex-specific placental transcriptome alterations in late-onset preeclampsia reveal male-biased immune and metabolic dysregulation

Preeclampsia is a hypertensive disorder of pregnancy with major maternal and fetal consequences. While the molecular basis of early-onset preeclampsia is well studied, the mechanisms underlying late-onset disease-and how they differ by fetal sex-remain poorly understood. Placental transcriptomic profiling at term can reveal persistent molecular alterations reflecting cumulative disease processes.

Replicating hypergraph disease dynamics with lower-order interactions

Disease spreading models such as the ubiquitous SIS compartmental model and its numerous variants are widely used to understand and predict the behavior of a given epidemic or information diffusion process. A common approach to imbue more realism to the spreading process is to constrain simulations to a network structure, where connected nodes update their disease state based on pairwise interactions along the edges of their local neighborhood. 

ASCIA Guideline: Infant Feeding for Food Allergy Prevention

The Australasian Society of Clinical Immunology and Allergy (ASCIA) Guideline: Infant Feeding for Food Allergy Prevention is an update of the 2016 ASCIA guideline. This updated guideline provides recommendations specifically in relation to infant feeding for food allergy prevention. 

Reducing Rates of Severe Hypoglycemia in a Population-Based Cohort of Children and Adolescents With Type 1 Diabetes Over the Decade 2000–2009

The objective of this study was to examine rates of severe hypoglycemia (SH) in a large population-based cohort of children with type 1 diabetes and...