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Hierarchy and molecular properties of house dust mite allergens

The allergenic load of house dust mite allergy is largely constituted by a few proteins with a hierarchical pattern of allergenicity.

The Infant Nasopharyngeal Microbiome Impacts Severity of Lower Respiratory Infection and Risk of Asthma Development

Lung inflammation resulting from ARIs during infancy is linked to asthma development.

A role for CCL28-CCR3 in T-cell homing to the human upper airway mucosa

Lymphocyte recruitment to peripheral tissues is fundamental for immune surveillance and homeostasis, but the chemokines and chemokine receptors responsible...

Identification of Der p 23, a peritrophin-like protein, as a new major dermatophagoides pteronyssinus allergen

The house dust mite (HDM) Dermatophagoides pteronyssinus is one of most important allergen sources and a major elicitor of allergic asthma.

Quantitation of IgE Binding to the Chitinase and Chitinase-Like House Dust Mite Allergens

The prevalence of IgE binding to the group 15 and 18 house dust mite (HDM) allergens of the Dermatophagoides species...

House dust allergy and immunotherapy

HDM allergy is associated with asthma, allergic rhinitis and atopic dermatitis.

Reduced rhinovirus-specific antibodies are associated with acute exacerbations of chronic obstructive

Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are often linked to respiratory infections.

The Western Environment Reduces Innate Immune Cytokine Production in Chinese Immigrants

We recruited age- and sex-matched Chinese immigrants living in Western Australia for less than 6 months (newly arrived, n = 22) or more than 5 years.

T-cell responses against rhinovirus species A and C in asthmatic and healthy children

Infections by RV species A and C are the most common causes of exacerbations of asthma and a major cause of exacerbations of other respiratory disease.

Clinical significance of circulating microRNAs as markers in detecting and predicting congenital heart defects in children

In this study, we aimed to investigate the usefulness of miRNAs as biomarkers in diagnosing and predicting children with congenital heart defects (CHD), particularly in the context of multiple subtypes of CHD.