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FEF25–75% trajectories from age 7 to 53 years, associations with childhood and parental preconception factors, and midlife COPD risk: a prospective cohort study

Existing trajectory studies have emphasised large-airway indices, but chronic obstructive pulmonary disease (COPD) might originate in smaller airways. This study aimed to investigate mid-to-small-airway function trajectories, their associated factors, and COPD risk.

The National Allergy Centre of Excellence–Addressing Australia's Allergy Burden

Australia has one of the highest rates of food allergy, anaphylaxis hospital admissions and anaphylaxis fatalities worldwide. These trends and sustained advocacy prompted a 2019 Parliamentary Inquiry into Allergies and Anaphylaxis. Among 250 submissions, the Centre for Food Allergy Research called for a national research-coordinating centre and comprehensive allergy research funding.

Acceptability and Utility of a Virtual Reality Diabetes-Related Foot Disease Training Program for First Nations People: A Pragmatic Quasi-Experimental Case Series Study

To test the utility and acceptability of a novel VR training tool for community health practitioners in assessing diabetes-related foot disease in Aboriginal and Torres Strait Islander people.

Body Mass Index Trajectories Among Patients with Drug-Susceptible and Drug-Resistant Tuberculosis in Northwest Ethiopia

A retrospective cohort study was conducted using clinical data from patients attending TB clinics at four public hospitals in Northwest Ethiopia. We modelled BMI trajectories after TB treatment initiation using linear mixed models, with adjustments for potential confounders.

Relationship between serum clozapine to N-desmethyclozapine ratio and cognitive performance among people with treatment-resistant schizophrenia

We evaluated the relationship of serum clozapine and N-desmethyl clozapine and their ratio and cognition among people with treatment-resistant schizophrenia, an area that has been sub-optimally researched. 

Associations Between Potential Listeria monocytogenes Exposure During Pregnancy and Infant Outcomes at Birth and Infant Delivery Resource Use: A Cross-Sectional Analysis in Australian Women

Pregnant women are at higher risk of contracting listeriosis, which can lead to serious perinatal complications. This study evaluated associations between Listeria monocytogenes exposure, infant perinatal outcomes, and hospital resource use in a cohort of 1604 Australian mother-infant dyads. 

Regulatory standardisation to improve the safety of continuous glucose monitoring systems in Australia and New Zealand: joint ADS/ADEA/ADIPS/ANZSPED/NZSSD statement

Self-monitoring of glycaemia is a cornerstone of diabetes management, particularly for people using insulin. Traditionally, glucose monitoring involved finger-pricking and measuring capillary blood glucose concentration. Continuous glucose monitors have revolutionised self-monitoring of glucose levels. 

Beyond bone: the emerging role of osteoclasts in immune regulation, leukemia development and following myeloablative therapy

Osteoclasts are important regulators of bone remodeling, with an established role in maintaining skeletal homeostasis. The emergence of osteoimmunology has identified osteoclasts as key players in the immune system. In particular, osteoclasts can initiate bi-directional crosstalk mechanisms with hematopoietic stem cells and various immune cells, such as T cells, B cells and NK cells, to influence hematopoiesis and inflammatory response.

A primary cell model of the very preterm epithelium reveals barrier defects at 1 year of age

Limited evidence suggests that airway epithelial structure and function is disrupted in very preterm infants; however, the epithelial morphology and physiology has not been well characterised following discharge from neonatal intensive care. This study aimed to characterise the nasal airway epithelium from 1-year-old survivors of very preterm birth.

Perspectives of LGBTQA+ young people on suicide prevention services in Australia

LGBTQA + people are less likely to access mental health care despite an increased risk of adverse mental health outcomes including suicidal thoughts and behaviours. The present study aimed to explore Australian LGBTQA + young people's perceptions of key factors associated with access to suicide prevention services.