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Research

A molecular dynamics study of C1r and C1s dimers: Implications for the structure of the C1 complex

Complement is an important part of the immune system. It is initiated through three different pathways known as the classical, lectin, and alternative pathway.

Research

Multiple sclerosis: A disease of affluence?

Multiple sclerosis is rare in tropical areas, but quite common in developed countries.

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Safety and Immunogenicity of Neonatal Pneumococcal Conjugate Vaccination in Papua New Guinean Children: A Randomised Controlled Trial

We conducted an open randomized controlled trial in Papua New Guinea to compare safety, immunogenicity and priming for memory of 7-valent PCV (PCV7) given in...

Research

Vitamin D and atopy and asthma phenotypes in children: a longitudinal cohort study

Vitamin D has been linked in some studies with atopy- and asthma-associated phenotypes in children with established disease,but its role in disease inception...

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No association between early gastrointestinal problems and autistic-like traits in the general population

No association between early gastrointestinal problems and autistic-like traits in the general population, determine whether gastrointestinal problems, early...

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Gene polymorphisms, breast-feeding, and development of food sensitization in early childhood

The effect of breast-feeding on the development of allergic disease is uncertain

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Reference values for spirometry: The way forward for our patients

Few clinical respiratory laboratories have assessed the impact of changing reference equations on the interpretation of spirometric outcomes.

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Validity and Psychometric Properties of the Early Development Instrument in Canada, Australia, United States, and Jamaica

There is an increasing support from international organizations and the research community for stepping beyond infant or child mortality as the most common...

Research

The associations between physical activity, screen time and weight from 6 to 14 yrs: The Raine Study

To examine the strength and direction of the relationship between physical activity level, screen use and BMI in a cohort at ages 6, 8, 10 and 14 yrs as part...