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Here we show that transfected macrophages stably expressing wild-type Nramp1 (Nramp1+) control the net replication of B. thailandensis, but not B. pseudomallei.
disease-deconvolution" identified associations between the parasite-brain interactions and epilepsy, movement disorders, Alzheimer's disease, and cancer.
These results contribute to our understanding of immunopathology associated with visceral leishmaniasis and response to sodium stibogluconate treatment
We found no increased risk of poor development among boys with hypospadias or undescended testis
We believe this data represents a useful resource to understand the central nervous system in macaque.
Our results show perturbation of host mitochondrial function following T. gondii infection that likely impacts on pathogenesis of disease.
We assessed 30 sibships and 89 parent/case trios of presumed ocular toxoplasmosis (POT) to evaluate associations with polymorphisms in the NOD2 gene.
We identified several novel candidate genes which warrant further analysis in cohorts matched more precisely for clinical phenotypes.
Otitis media (OM) is a common disease in early childhood characterised by inflammation of the middle ear.
This study examines whether polymorphisms in the ERBB2 gene were associated with leprosy in primary and replication cohorts from northeastern Brazil.