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UV exposure and protection against allergic airways diseaseAsthma is a chronic inflammatory disease of the small and large conducting airway mucosa characterised by Th2 cell immunity.
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Season, terrestrial ultraviolet radiation, and markers of glucose metabolism in children living in Perth, Western AustraliaIncreased safe sun exposure in winter therefore represents a plausible means of reducing fasting blood sugar in children with obesity
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The effects of in utero vitamin D deficiency on airway smooth muscle mass and lung functionIn this study, we aimed to uncover the molecular mechanisms contributing to altered lung structure and function.
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Toward homeostasis: Regulatory dendritic cells from the bone marrow of mice with inflammationInflammatory mediators from peripheral tissues may control dendritic cell (DC) development in the bone marrow.
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Vitamin D deficiency causes deficits in lung function and alters lung structureThe prevalence of vitamin D deficiency is increasing and has been linked to obstructive lung diseases including asthma and chronic obstructive pulmonary disease
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Gene regulation by 1,25-dihydroxyvitamin D3 in CD4+CD25+ cells is enabled by IL-2Vitamin D may be responsible for reducing the development and severity of autoimmune and allergic diseases. Topically applied 1,25-dihydroxyvitamin D(3) (1,25(O
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Immune-modifying properties of topical vitamin D: Focus on dendritic cells and T cellsTopical creams containing the active form of vitamin D (1,25-dihydroxyvitamin D3; 1,25(OH)2D3) or analogues of this compound are currently used with some succes
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Quantifying the effectiveness of betaherpesvirus-vectored transmissible vaccinesTransmissible vaccines have the potential to revolutionize how zoonotic pathogens are controlled within wildlife reservoirs. A key challenge that must be overcome is identifying viral vectors that can rapidly spread immunity through a reservoir population.
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Vitamin D supplementation of initially vitamin D-deficient mice diminishes lung inflammation with limited effects on pulmonary epithelial integrityIn disease settings, vitamin D may be important for maintaining optimal lung epithelial integrity and suppressing inflammation, but less is known of its effects prior to disease onset.
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Characterising nitric oxide-mediated metabolic benefits of low-dose ultraviolet radiation in the mouse: a focus on brown adipose tissueNon-burning (low-dose) UVR suppresses the BAT 'whitening', steatotic and pro-diabetic effects of consuming a high-fat diet through skin release of nitric oxide