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Despite our current treatment, many cystic fibrosis (CF) patients still show progressive bronchiectasis and small airways disease.

This paper is a review of lung function tests best suited to use for early detection of lung disease in Cystic Fibrosis.

Stratification of monitoring protocols based on the risk profile of the patient can help us in the future to better care for people with Cystic Fibrosis.

The aim of this study was to determine whether assessment of early CT scan-detected bronchiectasis in young children with cystic fibrosis (CF) depends on...

Clinical trials for the treatment of cystic fibrosis (CF) lung disease are important to test and optimise new therapeutic interventions.

To examine the distribution of early structural lung changes in clinically stable infants and young children with cystic fibrosis using chest computed...

Cystic fibrosis (CF) lung disease commences early in the disease progression and is the most common cause of mortality.

Cystic fibrosis related progressive lung disease characterised by inflammation and infection commences soon after birth.

A better understanding of the innate immune responses by CF airway epithelial cells is needed to identify why viral infections are more severe in CF

Comprehensive scores incorporating clinical, lung function, imaging and laboratory data will become essential in the future for predicting disease progression and for use in clinical trials