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The airway epithelium of children with wheeze is characterized by defective repair that contributes to disease pathobiology. Dysregulation of developmental processes controlled by Notch has been identified in chronic asthma. However, its role in airway epithelial cells of young children with wheeze, particularly during repair, is yet to be determined.
This chapter will discuss the structure of the airway highlighting the now broad number of cell types that comprise it
In this study, we aimed to investigate the usefulness of miRNAs as biomarkers in diagnosing and predicting children with congenital heart defects (CHD), particularly in the context of multiple subtypes of CHD.
Free NE activity is deleterious for epithelial homeostasis and support the hypothesis that proteases in the airway contribute to CF structural lung disease
The aim of this study was to assess if MMP activation positively correlates with neutrophil elastase activity, disease severity and bronchiectasis in young...
Vaccines including conserved antigens from Streptococcus pneumoniae & nontypeable Haemophilus influenzae have the potential to reduce of otitis media.
The Global Consortium of Oral Health Birth Cohort Studies (GLOBICS) is an international research network dedicated to advancing knowledge from Oral Health Birth Cohort Studies (OHBCS).
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April is Autism Month and to mark the occasion, we’re transforming our reception desk in the clinic to an AMAZING wall for our families to contribute to.
While COVID-19 is frightening, we've created some resources designed to help families tackle the challenges this virus has created for us.