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Research

Genetic Variants Associated with Increased Risk of Malignant Pleural Mesothelioma: A Genome-Wide Association Study

Asbestos exposure is the main risk factor for malignant pleural mesothelioma (MPM), a rare aggressive tumor.

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A novel retro-inverso peptide is a preferential JNK substrate-competitive inhibitor

A novel 18 amino acid peptide PYC98 was demonstrated to inhibit JNK1 activity toward c-Jun.

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A time series analysis of presentations to Queensland health facilities for alcohol-related conditions, following the increase in 'alcopops' tax

We measured changes in admissions for alcohol-related harm to health throughout Queensland, before and after the tax increase in April 2008.

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Cancer incidence and mortality among underground and surface goldminers in Western Australia

Overall cancer mortality and incidence was higher among Western Australian goldminers compared with the general male population, particularly for underground...

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The gap in life expectancy from preventable physical illness in psychiatric patients in Western Australia

Despite knowledge about excess mortality in people with mental illness, the gap in their life expectancy compared with the general population has widened...

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A systematic review of risk factors for cerebral palsy in children born at term in developed countries

The aim of this study was to conduct a systematic review in order to identify the risk factors for cerebral palsy (CP) in children born at term.

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The anti-inflammatory actions of IL-4 in human monocytes are not mediated by IL-10, RP105 or the kinase activity of RIPK2

The anti-inflammatory actions of IL-4 in activated human monocytes may reflect transcriptional regulation of genes involved in TLR signaling pathways.

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Suppression of adrenomedullin contributes to vascular leakage and altered epithelial repair during asthma

The anti-inflammatory peptide, adrenomedullin (AM), and its cognate receptor are expressed in lung tissue, but its pathophysiological significance in airway...

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Risk of childhood acute lymphoblastic leukaemia following parental occupational exposure to pesticides

Risk of childhood acute lymphoblastic leukaemia following parental occupational exposure to pesticides.

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Research performance evaluation: The experience of an independent medical research institute

Evaluation of the social and economic outcomes of health research funding is an area of intense interest and debate...