Search
Research
Mapping care provision for type 1 diabetes throughout Australia: a protocol for a mixed-method studyType 1 diabetes (T1D) is a chronic and incurable autoimmune disease, diagnosed in early childhood and managed initially in paediatric healthcare services. In many countries, including Australia, national audit data suggest that management and care of T1D, and consequently glycaemic control, are consistently poor.
Research
ISPAD Clinical Practice Consensus Guidelines 2022: Exercise in children and adolescents with diabetesLiz Davis MBBS FRACP PhD Co-director of Children’s Diabetes Centre Co-director of Children’s Diabetes Centre Professor Davis is a paediatric
Research
Suboptimal glycemic control in adolescents and young adults with type 1 diabetes from 2011 to 2020 across Australia and New Zealand: Data from the Australasian Diabetes Data Network registryCompeting challenges in adolescence and young adulthood can distract from optimal type 1 diabetes (T1D) self-management, and increase risks of premature morbidity and mortality. There are limited data mapping the glycemic control of people with T1D in this age group, across Australasia.
Research
Machine learning and clinical epigenetics: a review of challenges for diagnosis and classificationWe now have a growing number of epigenetic alterations in disease, and this offers a chance to increase sensitivity and specificity of future diagnostics and therapies
Research
Differential SLC6A4 methylation: a predictive epigenetic marker of adiposity from birth to adulthoodThese data suggest that altered methylation of CpG loci within SLC6A4 may provide a robust marker of adiposity across the life course
Research
In “high-risk” infants with sufficient vitamin d status at birth, infant vitamin D supplementation had no effect on allergy outcomes: A randomized controlled trialEarly infancy oral vitamin D supplementation does not appear to reduce the development of early childhood allergic disease
Research
A randomized comparison of three prandial insulin dosing algorithms for children and adolescents with Type 1 diabetesThe Pankowska Equation resulted in reduced postprandial hyperglycaemia at the expense of an increase in hypoglycaemia
Research
Unexpected Management Behaviors in Adolescents With Type 1 Diabetes Using Sensor-Augmented Pump TherapyConstant exposure to real-time data can lead to unsafe management responses in adolescents with the behavior influenced by trust or mistrust in the system
Research
The Importance of the Hawthorne Effect on Psychological Outcomes Unveiled in a Randomized Controlled Trial of Diabetes TechnologyThe objective of this communication is to highlight the Hawthorne effect on psychobehavioral measures and the importance of a control group in clinical research, particularly for diabetes technologies
Research
Differential DNA methylation of steatosis and non-alcoholic fatty liver disease in adolescenceEpigenetic modifications are associated with hepatic fat accumulation and non-alcoholic fatty liver disease (NAFLD). However, few epigenetic modifications directly implicated in such processes have been identified during adolescence, a critical developmental window where physiological changes could influence future disease trajectory. To investigate the association between DNA methylation and NAFLD in adolescence, we undertook discovery and validation of novel methylation marks, alongside replication of previously reported marks.