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Australia needs a single national pharyngitis guideline to assist in providing rational, consistent and timely antibiotic treatment to patients at high risk of ARF
We review the Group A Streptococcus Human infection studies and present the study protocol for a dose-ranging inpatient study in healthy adults
These results indicate that anaphylaxis is not a major cause of adverse reactions to benzathine penicillin G
This scoping review explores existing clinical guidelines on administration of benzathine benzylpenicillin (Bicillin L-A, Pfizer Australia) in Australia and Aotearoa New Zealand. The objective is to understand existing delivery guidance to address variation in care and cultural safety considerations, to support messaging during periods of stockout and to inform planning for new administration techniques.
Due to the ongoing impact of colonisation, Aboriginal and Torres Strait Islander people live with a greater burden of cardiovascular disease (CVD) than non-Indigenous Australians. Shared decision-making (SDM) is recognised as an essential component of person-centred care. However, there has been a lack of tools to support clinician communication and SDM to address CVD prevention in this important 'at-risk' population.
This study provides new knowledge on ARF characteristics and management and highlights international variation in diagnostic and management practice.
Language is significant for communicating knowledge across cultures and generations and has the power to attribute meanings and alter our worldviews.
The STARFISH (STopping Acute Rheumatic Fever Infections to Strengthen Health) program, funded by the NHMRC Synergy Grant, investigates the most effective environmental health initiatives (EHIs) to reduce Strep A infections and prevent ARF.
Understanding Strep A transmission within the home is critical to inform effective prevention strategies.
This Phase-IIa trial evaluates the safety and pharmacokinetics of high-dose, 10 weekly subcutaneous injections of penicillin (SCIP) in young people with a history of acute rheumatic fever (ARF).