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Research

Onset of maternal psychiatric disorders after the birth of a child with intellectual disability: A retrospective cohort study

Mothers of a child with intellectual disability (ID) have more psychiatric disorders after the birth of their child than other mothers.

Research

Folate pathway gene polymorphisms, maternal folic acid use, and risk of childhood acute lymphoblastic leukaemia

Several studies suggest that maternal folic acid supplementation before or during pregnancy protects against childhood acute lymphoblastic leukaemia (ALL).

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Patterns of depressive symptoms and social relating behaviors differ over time from other behavioral domains for young people with Down syndrome

People with intellectual disabilities are at a higher risk for experiencing behavioral, emotional, and psychiatric problems in comparison with the general...

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Aberrant expression of aldehyde dehydrogenase 1A (ALDH1A) subfamily genes in acute lymphoblastic leukaemia is a common feature of T-lineage tumours

The class 1A aldehyde dehydrogenase (ALDH1A) subfamily of genes encode enzymes that function at the apex of the retinoic acid (RA) signalling pathway.

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Maternal Alcohol Use and Sudden Infant Death Syndrome and Infant Mortality Excluding SIDS

The highest risk of SIDS occurred when a maternal alcohol diagnosis was recorded during pregnancy or within 1 year postpregnancy.

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Pleurodesis outcome in malignant pleural mesothelioma

Surgical pleurodesis showed no advantages over bedside pleurodesis in efficacy, patient survival or total time spent in hospital from procedure till death.

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Low positive predictive value of International Classification of Diseases, 10th Revision codes in relation to rheumatic heart disease: a challenge for global surveillance

We outline a series of research initiatives to improve identification of RHD in administrative data thereby contributing to monitoring the RHD burden globally

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Developing evidence-based recommendations for optimal interpregnancy intervals in high-income countries: Protocol for an international cohort study

We aim to assess the impact of interpregnancy intervals on maternal and child health outcomes in high-income countries

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Are children more vulnerable to mesothelioma than adults?

We found no greater susceptibility to mesothelioma among those first exposed to asbestos as children than those first exposed as adults