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Large numbers of children need emergency medical treatment each year for respiratory illnesses, particularly for wheezing and asthma.
An NHMRC grant exploring epigenetic factors that affect wheezing and asthma development.
The epithelium is integral to the protection of many different biological systems and for the maintenance of biochemical homeostasis. Emerging evidence suggests that particular children have epithelial vulnerabilities leading to dysregulated barrier function and integrity, that resultantly contributes to disease pathogenesis.