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Structural and IgE binding analyses of recombinant Der p 2 expressed from the hosts Escherichia coli and Pichia pastorisThe house dust mite allergen Der p 2 is one of the most important indoor allergens associated with allergic disease.
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Family Study of Ear Health and Metabolic Diseases in a Western Australian Aboriginal CommunityTo determine whether these extreme manifestations of disease are associated with rare or novel genetic variants in a Western Australian Aboriginal population.
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Arylsulphatase A Pseudodeficiency (ARSA-PD), hypertension and chronic renal disease in Aboriginal AustraliansTraits associated with CVD, CRD and T2D in Aboriginal Australians provide novel insight into function of Arylsulphatase A Pseudodeficiency variants
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Association between male genital anomalies and adult male reproductive disorders: a population-based data linkage study spanning more than 40 yearsWe provide new evidence to support current guidelines for orchidopexy before age 18 months to decrease the risk of future testicular cancer and infertility
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Maternal and umbilical cord androgen concentrations do not predict digit ratio (2D:4D) in girls:Digit ratio (2D:4D) is widely used as a marker of prenatal androgen exposure
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The -2518bp promoter polymorphism at CCL2/MCP1 influences susceptibility to mucosal but not localizedMucosal leishmaniasis (ML) follows localized cutaneous leishmaniasis (CL) caused by Leishmania braziliensis.
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Reference exome data for Australian Aboriginal populations to support health-based researchOur data set provides a useful reference point for genomic studies on Aboriginal Australians
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Genetics, Transcriptomics and Meta-Taxonomics in Visceral LeishmaniasisVisceral leishmaniasis (VL) caused by parasites of the Leishmania donovani complex can be fatal in susceptible individuals. Understanding the interactions between host and pathogen is one way to obtain leads to develop better drugs and for vaccine development. In recent years multiple omics-based approaches have assisted researchers to gain a more global picture of this interaction in leishmaniasis. Here we review results from studies using three omics-based approaches to study VL caused by L. donovani in India.
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FANTOM5 CAGE profiles of human and mouse samplesResulting data represents the consequence of transcriptional regulation in each analyzed state of mammalian cells.
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Prevalence and risk factors for parent-reported recurrent otitis media during early childhoodThe prevalence of parent-reported rOM was 26.8% (611/2280) and 5.5% (125/2280) for severe rOM in the Study.