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Research
Potential immunological effects of gender-affirming hormone therapy in transgender people – an unexplored area of researchThere are well-described sex-based differences in how the immune system operates. In particular, cisgender (cis) females have a more easily activated immune system; associated with an increased prevalence of autoimmune diseases and adverse events following vaccinations. Conversely, cis males have a higher threshold for immune activation, and are more prone to certain infectious diseases, such as coronavirus disease (COVID-19).
Research
Complications associated with paediatric airway management during the COVID-19 pandemic: an international, multicentre, observational studyRespiratory adverse events in adults with COVID-19 undergoing general anaesthesia can be life-threatening. However, there remains a knowledge gap about respiratory adverse events in children with COVID-19. We created an international observational registry to collect airway management outcomes in children with COVID-19 who were having a general anaesthetic.
Research
Validation of a rapid, saliva-based, and ultra-sensitive SARS-CoV-2 screening system for pandemic-scale infection surveillanceWithout any realistic prospect of comprehensive global vaccine coverage and lasting immunity, control of pandemics such as COVID-19 will require implementation of large-scale, rapid identification and isolation of infectious individuals to limit further transmission. Here, we describe an automated, high-throughput integrated screening platform, incorporating saliva-based loop-mediated isothermal amplification (LAMP) technology, that is designed for population-scale sensitive detection of infectious carriers of SARS-CoV-2 RNA.
News & Events
COVID tests well tolerated by WA school kidsA study conducted across 40 WA schools has found COVID-19 testing using a combined nose and throat swab was well tolerated by children as young as 4 years.
News & Events
Minderoo Foundation funds vaccine trial to protect WA healthcare workers from COVID-19At least 2,000 WA healthcare workers will help test whether an existing tuberculosis vaccine can reduce their chance of COVID-19 infection, lessen the severity of symptoms and boost immunity.
News & Events
Community advocate jumps on board with new COVID-19 advisory groupLike many of us, consumer and community advocate Catherine Hughes is worried about the impact of COVID-19. So she joined Australia’s first COVID-19 consumer reference group to be a voice for the community.
News & Events
Rapidly assembled advisory group to offer community take on COVID-19 researchThe speed with which research projects on the coronavirus have been put together has consumer advocates concerned that a vital voice will be missing – that of the community.
Research
Convalescent plasma in hospitalised patients with COVID-19Convalscent plasma (CP) was identified as a potential therapy for COVID-19 available early in the pandemic.
Research
Understanding motivation and experience in participating in a paediatric SARS-CoV-2 serosurvey, in AustraliaSerosurveys are considered as a valuable tool in estimating population immunity and infection rates but recruitment of children to provide paediatric estimates can be challenging. A novel approach of sampling children undergoing anaesthesia was utilised for a SARS-CoV-2 serosurvey in Australian children and we explore the reasons for participation, feedback on the approach and importance of research into Coronavirus Diseases 2019 (COVID-19).
The Kids Research Institute Australia answers all of your questions about vaccines and children