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Our team uses AI to quickly analyse large amounts of genetic data to help discover alternate medications and improve existing treatments.
Research
Recognition and Management of Protracted Bacterial Bronchitis in Australian Aboriginal Children: A Knowledge Translation ApproachChronic wet cough in children is the hallmark symptom of protracted bacterial bronchitis (PBB) and if left untreated can lead to bronchiectasis, which is prevalent in Indigenous populations. Underrecognition of chronic wet cough by parents and clinicians and underdiagnosis of PBB by clinicians are known.
Research
A pilot study of disease related education and psychotherapeutic support for unresolved grief in parents of children with CFDiagnosis of chronic disease in a child can result in unresolved grief (UG) in parents. This study aimed to evaluate the efficacy of psychological insight-oriented therapy (IOT) as a treatment for UG compared to disease related education in parents of children with cystic fibrosis. Sequence of delivery, first IOT then disease related education (or vice versa) was also examined, to let all participants experience both interventions.
Research
Macrophage PD-1 associates with neutrophilia and reduced bacterial killing in early cystic fibrosis airway diseaseMacrophages are the major resident immune cells in human airways coordinating responses to infection and injury. In cystic fibrosis, neutrophils are recruited to the airways shortly after birth, and actively exocytose damaging enzymes prior to chronic infection, suggesting a potential defect in macrophage immunomodulatory function.
Research
Current understanding of the neutrophil transcriptome in health and diseaseNeutrophils are key cells of the innate immune system. It is now understood that this leukocyte population is diverse in both the basal composition and functional plasticity. Underlying this plasticity is a post-translational framework for rapidly achieving early activation states, but also a transcriptional capacity that is becoming increasingly recognized by immunologists.
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News & Events
World-first study finds some biodiesel exhausts harmful to childrenWal-yan Respiratory Research Centre PhD candidate Katherine Landwehr is researching the impact of breathing in biodiesel exhaust fumes on the lungs.
News & Events
Great minds come together at Wal-yan Scientific RetreatWal-yan Respiratory Research Centre team members and special guests travelled to Wadjemup (Rottnest) on 27 and 28 October to spend an intensive two days together learning about, and providing input into, the broad range of research projects underway within the Centre.
News & Events
Patients with antibiotic-resistant lung infections to receive promising phage therapy treatment as part of new trial led by The Kids Research Institute Australia Researcher Anthony KicicPatients with lung infections that are not responding to antibiotics will be treated with phage therapy as part of a translational trial program to be undertaken by world-recognised experts in this field.