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Real-world outcomes of insulin pump compared to injection therapy in a population-based sample of children with type 1 diabetesPatients using insulin pump therapy had a better long-term glycemic control relative to the matched injection therapy cohort
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Use of Continuous Glucose Monitoring Trends to Facilitate Exercise in Children with Type 1 DiabetesThis study investigated the use of a carbohydrate intake algorithm based on continuous glucose monitoring trends during physical activity
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Effect of combining pre-exercise carbohydrate intake and repeated short sprints on the blood glucose response to exercise in young individuals with Type 1 diabetesWhen carbohydrates are ingested prior to moderate-intensity exercise, adding repeated sprints is not significantly detrimental to glycaemic management
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Maternal body mass index, gestational weight gain, and the risk of overweight and obesity across childhood: An individual participant data meta-analysisHigher maternal pre-pregnancy BMI and gestational weight gain were associated with an increased risk of childhood overweight/obesity
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Effect of obesity on neonatal hypoglycaemia in mothers with gestational diabetes: A comparative studyTo determine the influence of obesity on neonatal hypoglycaemia among infants born to gestational diabetes mellitus mothers.
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Use of linked administrative and laboratory data to confirm that serum 25(OH)D levels in pregnant women can be predicted from satellite estimates of ultraviolet radiationSerum 25 hydroxyvitamin D [25(OH)D] levels of pregnant women have been linked to various health outcomes in their offspring. Satellite-derived ultraviolet radiation (UVR) data have been used as a proxy for 25(OH)D levels, as individual-level cohort studies are time-consuming, costly and only feasible for common outcomes.
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The challenges of developing and optimising an assay to measure 25-hydroxyvitamin D in salivaWe have developed an LC-MS/MS assay that accurately measures saliva 25(OH)D3 levels, which correlated with serum levels
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A very low carbohydrate diet for minimising blood glucose excursions during ultra-endurance open-water swimming in type 1 diabetes: a case reportCarbohydrate-restricted diets are used by people with type 1 diabetes (T1D) to help manage their condition. However, the impact of this strategy on blood glucose responses to exercise is unknown. This study describes the nutritional strategies of an athlete with T1D, who follows a very low carbohydrate diet to manage her condition during an ultra-endurance open-water swimming event.
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Type 1 DiabetesA lifelong auto-immune condition that can affect anyone, but is most commonly diagnosed in childhood.
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A microRNA-based dynamic risk score for type 1 diabetesIdentifying individuals at high risk of type 1 diabetes (T1D) is crucial as disease-delaying medications are available. Here we report a microRNA (miRNA)-based dynamic (responsive to the environment) risk score developed using multicenter, multiethnic and multicountry ('multicontext') cohorts for T1D risk stratification. Discovery (wet and dry lab) analysis identified 50 miRNAs associated with functional β cell loss, which is a hallmark of T1D.