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Early respiratory infection is associated with reduced spirometry in children with cystic fibrosisWe hypothesized that the presence of these markers of cystic fibrosis lung disease in the first 2 years of life would be associated with reduced lung...
Research
Smoking during pregnancy, vitamin C supplementation, and infant respiratory healthThis article discusses the merits and potential shortcomings of a study reported previously showing that giving Vitamin C to women who smoked during...
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Evaluating hypoxia during air travel in healthy infantsUp to a third of ex-preterm infants flying near term exhibit pulse oxygen saturation (SpO2) of less than 85% during air travel.
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Respiratory Health ProgramListed are The Kids Research Institute Australia research teams involved in our Respiratory Health Program. This program sits under the Chronic and Severe Diseases research theme.
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Transcriptomic analysis of primary nasal epithelial cells reveals altered interferon signalling in preterm birth survivors at one year of ageMany survivors of preterm birth (<37 weeks gestation) have lifelong respiratory deficits, the drivers of which remain unknown. Influencers of pathophysiological outcomes are often detectable at the gene level and pinpointing these differences can help guide targeted research and interventions. This study provides the first transcriptomic analysis of primary nasal airway epithelial cells in survivors of preterm birth at approximately 1 year of age.
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Effectiveness of current digital cognitive behavioural therapy for insomnia interventions for adolescents with insomnia symptoms: A systematic review and meta-analysisSleep problems occur in up to 20%-45% of adolescents. This systematic review and meta-analysis examined the effectiveness of digital sleep interventions, based on cognitive behavioural therapy for insomnia, for adolescents with insomnia symptoms. The objective was to synthesise and quantify, through meta-analyses, changes in sleep following completion of a digital sleep-based intervention.
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Survey of clinical infant lung function testing practicesTo evaluate current ILF testing practices and to survey users regarding the indications, limitations and perceived clinical benefits of ILF testing.
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The ventilatory response to hypoxia is blunted in some preterm infants during the second year of lifePreterm birth and subsequent neonatal ventilatory treatment disrupts development of the hypoxic ventilatory response (HVR). An attenuated HVR has been identified in preterm neonates, however it is unknown whether the attenuation persists into the second year of life.
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Expression of bronchodilator response using forced oscillation technique measurements: absolute versus relativeExpression of bronchodilator response using forced oscillation technique measurements: absolute versus relative