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Research

Validation of monoclonal anti-PKC isozyme antibodies for flow cytometry analyses in human T cell subsets and expression in cord blood T cells

We have undertaken to validating the specificity of commercially available antibodies marketed for flow cytometry to measure PKCα, βI, βII, δ, ε, η, θ, ζ, ι/λ and μ

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Each meal matters in the exposome: Biological and community considerations in fast-food-socioeconomic associations

As we discuss, equal weekly visits to major fast-food outlets by the affluent and deprived do not translate into biological equivalency.

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Bugging allergy; role of pre-, pro- and synbiotics in allergy prevention

Here, we summarize and discuss findings of randomized clinical trials that have examined the effects of these strategies on short and long-term.

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Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics

Consistent with the original model of prebiotics, but aware of the latest scientific and clinical developments, the panel updated the definition of a prebiotics

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Effects of maternal n-3 fatty acid supplementation on placental cytokines, pro-resolving lipid mediators and their precursors

The aim of this study was to determine whether supplementation with fish oil-derived n-3 PUFA during pregnancy modifies modifies placental PUFA composition...

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Developing primary intervention strategies to prevent allergic disease

Allergic diseases are a major cause of morbidity in the developed world, now affecting up to 40 % of the population with no evidence that this is abating.

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The maturation of immune functions in pregnancy and early childhood

This book chapter explains the maturation of immune functions during pregnancy & in early childhood, and addresses the importance of early environmental...

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Does docosahexaenoic acid supplementation in term infants enhance neurocognitive functioning in infancy?

The proposal that dietary docosahexaenoic acid (DHA) enhances neurocognitive functioning in term infants is controversial.

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Gut microbiome and innate immune response patterns in IgE-associated eczema

Gut microbiome patterns have been associated with predisposition to eczema potentially through modulation of innate immune signalling.

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Maternal fish oil supplementation in pregnancy: a 12 year follow-up of a randomised controlled trial.

We aimed to investigate the long-term effects (12 years) of fish oil supplementation in pregnancy on neurodevelopment, including cognition, language and fine...