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Dietary protein affects both the dose and pattern of insulin delivery required to achieve postprandial euglycaemia in Type 1 diabetes: a randomized trialA high-protein meal requires ~50% more insulin to maintain euglycaemia than a low-protein meal that contains the same quantity of carbohydrate
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Common Pathways to NSSI and Suicide Ideation: The Roles of Rumination and Self-CompassionThe salience of self-compassion offers promise for early intervention initiatives focusing on less judgmental or self-critical means of self-relation
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Community-based participatory action research on rheumatic heart disease in an Australian Aboriginal homeland: Evaluation of the ‘On track watch’ projectBased in 'both-way learning', the aim of this study was to co-design, implement and evaluate community-based participatory action research to achieve this vision
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Local Housing Characteristics Associated with Early Childhood Development Outcomes in Australian Disadvantaged CommunitiesAccess to safe, secure, and stable housing is a well-known social determinant of health
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Persistent negative symptoms in individuals at Ultra High Risk for psychosisPersistent negative symptoms can be detected early, allowing for the identification of a subset of Ultra High Risk patients who are likely to have poor outcome
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Commissioning and performance characteristics of a pre-clinical image-guided radiotherapy systemCharacteristics of a small-animal radiotherapy device, the X-RAD SmART, are described following commissioning of the device for pre-clinical radiotherapy research
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Tissue-resident memory T cells orchestrate tumour-immune equilibriumOur findings provide insight into the immune cell populations important for maintaining long-term tumour dormancy in peripheral tissues
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Sulfamethoxazole-Trimethoprim (Cotrimoxazole) for Skin and Soft Tissue Infections Including Impetigo, Cellulitis, and AbscessWe conducted a systematic review of clinical trials and observational studies that address the utility of SXT for SSTI treatment, caused by either GAS or MRSA
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Genome-Wide Analysis of Genetic Risk Factors for Rheumatic Heart Disease in Aboriginal Australians Provides Support for Pathogenic Molecular MimicryRheumatic heart disease (RHD) after group A streptococcus (GAS) infections is heritable and prevalent in Indigenous populations. Molecular mimicry between human and GAS proteins triggers proinflammatory cardiac valve-reactive T cells.
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Rationale and methods of a randomized controlled trial of immunogenicity, safety and impact on carriage of pneumococcal conjugate and polysaccharide vaccines in infants in Papua New GuineaVaccination trials in high endemicity areas are needed to provide evidence and guidance on idea strategies to protect children in these areas against infections