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Research
Oestrogen amplifies pre-existing atopy-associated Th2 bias in an experimental asthma modelThe role of oestrogen in experimental atopic asthma, and guide future research on sex-related variations in atopic asthma susceptibility/intensity
Research
Transplacental Innate Immune Training via Maternal Microbial Exposure: Role of XBP1-ERN1 Axis in Dendritic Cell Precursor ProgrammingWe recently reported that offspring of mice treated during pregnancy with the microbial-derived immunomodulator OM-85 manifest striking resistance to allergic airways inflammation, and localized the potential treatment target to fetal conventional dendritic cell (cDC) progenitors. Here, we profile maternal OM-85 treatment-associated transcriptomic signatures in fetal bone marrow, and identify a series of immunometabolic pathways which provide essential metabolites for accelerated myelopoiesis.
Research
RSV prophylaxis use in high-risk infants in Western Australia, 2002-2013: a record linkage cohort studyThe monoclonal antibody, palivizumab is licensed for use in high-risk infants to prevent severe illness caused by respiratory syncytial virus (RSV). The level of its use and compliance with current jurisdictional guidelines which were amended in 2010, is unknown.
Research
Prevalence of Mental Disorders Among Children and Adolescents of Parents with Self-Reported Mental Health ProblemsThis paper provides Australian population-level estimates of the prevalence of parental self-reported lifetime mental disorders and past 12 month mental disorders in their children
News & Events
New collaboration to boost kids early childhood development outcomes across AustraliaA new collaboration has been launched to fast track research into action to improve outcomes in the crucial early years of child development and learning.
Research
Developing a ‘Food Atlas’ for Western Australia to map, measure and monitor food accessThis unique interdisciplinary project, funded by Healthway, aims to develop a Food Atlas tool for mapping, measuring, and monitoring food access across Western Australia.
Research
Maximising fathers’ roles in preventing adolescent alcohol-related harm. (Fathers and Adolescent Alcohol Use Project)This project will explore fathers’ attitudes and behaviours regarding the alcohol-related parenting of 10-17-year-old children.
Research
The CliniBank Study: A research project to improve future clinical supports for children experiencing developmental difficultiesAndrew Gemma Gail Videos Whitehouse Watch and listen to Andrew Upson Alvares PhD BSc MClinAud MBA PhD Deputy Director (Research); Angela Wright
News & Events
Landmark research investigating benefits of COVID-19 vaccination for kids set to launch at The Kids Research Institute AustraliaA first-of-its-kind national study looking at the optimal COVID-19 vaccination strategies for children and adolescents is set to begin at Perth’s The Kids Research Institute Australia thanks to a $3.8 million funding injection from the Australian Government’s Medical Research Future Fund (MRFF).
Research
Quantification of Serum Ovalbumin-specific Immunoglobulin E Titre via in vivo Passive Cutaneous Anaphylaxis AssayWe describe herein a highly reproducible in vivo passive cutaneous anaphylaxis assay using Sprague Dawley rats for the quantification of ovalbumin-specific IgE