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Research
Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotypePrevious analyses of family data from the Tasmanian Longitudinal Health Study provide evidence that this phenotype has a stronger genetic cause than asthma...
Research
Hierarchy and molecular properties of house dust mite allergensThe allergenic load of house dust mite allergy is largely constituted by a few proteins with a hierarchical pattern of allergenicity.
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Toward improved prediction of risk for atopy and asthma among preschoolers: A prospective cohort studyAtopy and asthma are commonly initiated during early life, and there is increasing interest in the development of preventive treatments for at-risk children.
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Providing feedback on adherence increases use of preventive medication by asthmatic childrenThis study investigates the impact of measuring adherence and providing feedback on medication usage by children with unstable asthma.
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Prenatal adverse life events increase the risk for atopic diseases in children, which is enhanced in the absence of a maternal atopic predispositionThere is evidence to suggest an association between prenatal maternal stress and the development of asthma or other atopic diseases in offspring.
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UV exposure and protection against allergic airways diseaseAsthma is a chronic inflammatory disease of the small and large conducting airway mucosa characterised by Th2 cell immunity.
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Do early-life viral infections cause asthma?Epidemiologic associations between viral lower respiratory infections (LRIs) and asthma in later childhood are well known
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Viral infections and atopy in asthma pathogenesis: New rationales for asthma prevention and treatmentProspective birth cohort studies tracking asthma initiation and consolidation in community cohorts have identified viral infections occurring against a...
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Vitamin D 3 deficiency enhances allergen-induced lymphocyte responses in a mouse model of allergic airway diseaseIn this study, using a mouse model, we determined whether vitamin D deficiency in utero and during early life modulated the severity of asthma.
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Severity and persistence of asthma and mental health: a birth cohort studyThe goal of the current study was to investigate asthma and mental health among youth in the community.