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Despite advances in asthma therapeutics, the burden remains highest in preschool children; therefore, it is critical to identify primary care tools that distinguish preschool children at high risk for burdensome disease for further evaluation.
Bronchiectasis (not related to cystic fibrosis) is a chronic lung disease caused by a range of etiologies but characterized by abnormal airway dilatation, recurrent respiratory symptoms, impaired quality of life and reduced life expectancy.
Recent studies have demonstrated that some children with acute bronchiolitis can be successfully managed using home oxygen therapy.
The aim of this study was to document the likely interpretative effects of changing from commonly used current spirometry reference equations to the GLI2012...
Cystic fibrosis (CF) lung disease commences early in the disease progression and is the most common cause of mortality.
We aimed to ascertain the fit of the European Respiratory Society Global Lung Initiative 2012 reference ranges to contemporary Australasian spirometric data.
Prediction bias in spirometry reference equations can arise from combining equations for different age groups,...
Bronchiectasis is a chronic lung disease that impairs quality of life and reduces life expectancy.
Preterm birth is associated with lifelong respiratory sequelae, yet our understanding of lung function trajectories across the lifespan remains limited. We aimed to identify patterns of spirometry development from childhood to early adulthood in survivors of very preterm birth using novel data-driven methods.
Limited evidence suggests that airway epithelial structure and function is disrupted in very preterm infants; however, the epithelial morphology and physiology has not been well characterised following discharge from neonatal intensive care. This study aimed to characterise the nasal airway epithelium from 1-year-old survivors of very preterm birth.