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Research

Impact of the COVID-19 pandemic on long-term trends in the prevalence of diabetic ketoacidosis at diagnosis of paediatric type 1 diabetes: an international multicentre study based on data from 13 national diabetes registries

An increased prevalence of diabetic ketoacidosis at diagnosis of type 1 diabetes in children was observed in various diabetes centres worldwide during the COVID-19 pandemic. We aimed to evaluate trends in the prevalence of diabetic ketoacidosis at diagnosis of paediatric type 1 diabetes before and during the COVID-19 pandemic, and to identify potential predictors of changes in diabetic ketoacidosis prevalence during the pandemic.

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Clinical evaluation of a noninvasive alarm system for nocturnal hypoglycemia

The aim of this study was to evaluate the performance of a prototype noninvasive alarm system (HypoMon) for the detection of nocturnal hypoglycemia.

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Western Australian Children’s Diabetes Database

This register was established at Princess Margaret Hospital in 1987 which stores data on all consenting patients attending the hospital’s diabetes clinic.

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Epidemiology of T2DM in childhood and associated disease complications

Investigating the incidence of childhood Type 2 Diabetes in the Western Australian community

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Intranasal Insulin Trial II

If successful, this vaccine could prevent type 1 diabetes and the need for daily insulin injections in people at risk.

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Adolescent type 1 diabetes cardio-renal Intervention trial

An international clinical trial looking at intervention with Angiotensin Converting Enzyme Inhibitors (ACEI), Statins, or a combination of both

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Safety evaluation of closed loop system during hypoglyaemic stimuli

The purpose of this study is to evaluate the safety of new system called the Medtronic MinimedTM 670G that has been designed for long term outpatient use.

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Long-term cost-effectiveness of Dexcom G6 real-time continuous glucose monitoring system in people with type 1 diabetes in Australia

Real-time continuous glucose monitoring allows patients with diabetes to adjust insulin dosing, potentially improving glucose control. This study aimed to compare the long-term cost-effectiveness of the Dexcom G6 rt-CGM device versus self-monitoring of blood glucose and flash glucose monitoring in Australia in people with type 1 diabetes.

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Clinical practice guidelines for paediatric X-linked hypophosphataemia in the era of burosumab

X-linked hypophosphataemia (XLH), the most common inherited form of rickets, is caused by a PHEX gene mutation that leads to excessive serum levels of fibroblast growth factor 23 (FGF23). This leads to clinical manifestations such as rickets, osteomalacia, pain, lower limb deformity and overall diminished quality of life.

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The Impact of Externally Worn Diabetes Technology on Sexual Behavior and Activity, Body Image, and Anxiety in Type 1 Diabetes

Wearable technologies impact upon sexual activity and this influences the decision to adopt the technology