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Research

Epidemiology and risk factors for recurrent severe lower limb cellulitis: a longitudinal cohort study

Severe lower leg cellulitis recurrences are frequent, and each episode increases the likelihood of subsequent recurrence and length of hospitalization

Research

END RHD Community Project - Kimberley (Rheumatic Fever Strategy)

Dylan John Jonathan Rosemary Barth Jacky Carapetis AM Wyber B.Tech, MPH, PhD AM MBBS FRACP FAFPHM PhD FAHMS MBChB MPH FRACGP PhD Honorary Research

Research

Improving delivery of secondary prophylaxis for rheumatic heart disease

Jonathan Carapetis AM AM MBBS FRACP FAFPHM PhD FAHMS Executive Director; Co-Head, Strep A Translation; Co-Founder of REACH 08 6319 1000 contact@

Research

RHD Action

Rosemary Sophie Jonathan Wyber La Vincente Carapetis AM MBChB MPH FRACGP PhD BPsych (Hons) MAppEpi PhD AM MBBS FRACP FAFPHM PhD FAHMS Senior Research

Research

Global, regional, & national burden of rheumatic heart disease, 1990-2015

We estimated the global disease prevalence of and mortality due to rheumatic heart disease over a 25-year period

Research

Lessons learned in the development of sustained release penicillin drug delivery systems for the prophylactic treatment of rheumatic heart disease (RHD)

The current prophylactic treatment to prevent rheumatic heart disease requires four-weekly intramuscular injection of a suspension of the poorly soluble benzathine salt form of penicillin G (BPG) often for more than 10 years. In seeking to reduce the frequency of administration to improve adherence, biodegradable polymer matrices have been investigated.

Research

Calculation of the age of the first infection for skin sores and scabies in five remote communities in northern Australia

Prevalence of skin sores and scabies in remote Australian Aboriginal communities remains unacceptably high, with Group A Streptococcus (GAS) the dominant pathogen. We aim to better understand the drivers of GAS transmission using mathematical models.

Research

Prevention of rheumatic fever and heart disease: Nepalese experience

Historically, many young people suffered severe valvular disease and died awaiting heart valve replacement.

Research

Standardising and assessing digital images for use in clinical trials: A practical, reproducible method that blinds the assessor to treatment allocation

We describe the development and evaluation of a protocol for digital image collection by the non-professional photographer in a remote setting research trial