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Strep A causes a huge global burden of disease, from sore throats to rheumatic heart disease. Our team is developing a computer simulation model, OpenStrepA, to help researchers tackle this disease.
In 2020, we celebrated our 30th birthday with those who matter most — the kids whose lives we’ve changed through the research we do.
Meta-analyses and single-site studies have established that children are less infectious than adults within a household when positive for ancestral SARS-CoV-2. In addition, children appear less susceptible to infection when exposed to ancestral SARS-CoV-2 within a household. The emergence of SARS-CoV-2 variants of concern (VOC) has been associated with an increased number of paediatric infections worldwide.
Maternal stressful life events during pregnancy have been associated with immune dysregulation and increased risk for asthma and atopy in offspring. Few studies have investigated whether prenatal stress is associated with increased overall or specific infectious diseases in childhood, nor explored sex differences. We sought to examine the relationship between the nature and timing of maternal stress in pregnancy and hospitalisation with infection in offspring.
Our study provides evidence for geographic clustering of tuberculosis/human immunodeficiency virus co-infection in Ethiopia
Pneumococcal nasopharyngeal carriage prevalence and density were higher in infants delivered vaginally compared with those delivered by cesarean birth
We emphasize that barriers to planetary health and the clinical application of lifestyle medicine are maintaining an unhealthy status quo
Our data provide insight into the molecular mechanisms underpinning the association of HLA-DRB1 alleles with risk versus protection in visceral leishmaniasis in humans
People with intellectual disability were more likely to experience potentially preventable conditions at the end of their lives
Here we focus on more recent well-powered genome-wide association studies, including malaria, leprosy, tuberculosis, and visceral leishmaniasis