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Reports and Findings

Group A Streptococcus M1T1 Intracellular Infection of Primary Tonsil Epithelial Cells Dampens Levels of Secreted IL-8 Through the Action of SpyCEP

Our results suggest that intracellular infection with the pathogenic GAS M1T1 clone induces a strong pro-inflammatory response in primary tonsil epithelial cells

Older age is associated with a reduced likelihood of ambulance transport to a trauma centre after major trauma in Perth

Older adults who were not transported to the trauma centre had an increased odds of in-hospital mortality

Mucormycosis in Children: Review and Recommendations for Management

we summarize the literature on the epidemiology and diagnosis of this invasive fungal infection and provide suggestions on the management of mucormycosis in children

Hypospadias Prevalence and Trends in International Birth Defect Surveillance Systems, 1980–2010

We report on the prevalence and trends of hypospadias which indicate that the prevalence of hypospadias continues to increase internationally

Effects of Dietary Acute Tryptophan Depletion (ATD) on NPY Serum Levels in Healthy Adult Humans Whilst Controlling for Methionine Supply-A Pilot Study

Acute tryptophan depletion, and therefore, diminished substrate availability for brain 5-HT synthesis did not lead to significant changes in serum neuropeptide Y concentrations over time

Invasive fungal infections in children with acute lymphoblastic leukaemia: Results from four Australian centres, 2003-2013

Invasive fungal infections are more common in children with high-risk acute lymphoblastic leukaemia and in relapsed disease

The glycaemic benefits of a very-low-carbohydrate ketogenic diet in adults with Type 1 diabetes mellitus may be opposed by increased hypoglycaemia risk and dyslipidaemia

This study provides the first evidence that, ketogenic diets in adults with Type 1 diabetes are associated with excellent HbA1c levels and little glycaemic variability

Parental occupational exposure to low-frequency magnetic fields and risk of leukaemia in the offspring: Findings from the Childhood Leukaemia International Consortium

We did not find any associations between parental occupational extremely low-frequency magnetic fields exposure and childhood leukaemia

Effectiveness of a 3 + 0 pneumococcal conjugate vaccine schedule against invasive pneumococcal disease among a birth cohort of 1.4 million children in Australia

Our population-based cohort study demonstrates that >90% coverage in the first year of a universal 3 + 0 PCV program provided high population-level protection

Dysbiotic drift and biopsychosocial medicine: how the microbiome links personal, public and planetary health

Here we focus on the rapidly progressing microbiome science as a way to illustrate the pathways by which exposure to biodiversity supports health

Overcoming the challenges of caring for a child with foetal alcohol spectrum disorder: a Pilbara community perspective

The caregivers in this study have gained valuable knowledge and wisdom through caring for a child with FASD

Strep A (Group A Streptococcus)

Streptococcus A is a bacterium often found in the throat and on the skin.

Soy Biodiesel Exhaust is More Toxic than Mineral Diesel Exhaust in Primary Human Airway Epithelial Cells

Exposure to biodiesel exhaust resulted in significantly greater cell death and a greater release of immune mediators compared to both air controls and ULSD exhaust

Healthy population ageing depends on investment in early childhood learning and development

Interventions in the early years provide a sustainable solution by generating long-term labour productivity and social welfare benefits

Children of parents who have been hospitalised with psychiatric disorders are at risk of poor school readiness

Children of parents who have been hospitalised with psychiatric disorders are at risk for poor school readiness

Autism and psychosis: Clinical implications for depression and suicide

This study examines the association of autism spectrum traits, depressive symptoms and suicidal behaviour in individuals with psychotic experiences

Persistent induction of goblet cell differentiation in the airways: Therapeutic approaches

Here we review the current knowledge of key molecular pathways that are dysregulated during persistent goblet cell differentiation