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Topical antibiotics for chronic suppurative otitis media

Chronic suppurative otitis media (CSOM), sometimes referred to as chronic otitis media, is a chronic inflammation and often polymicrobial infection (involving more than one micro-organism) of the middle ear and mastoid cavity, characterised by ear discharge (otorrhoea) through a perforated tympanic membrane. The predominant symptoms are ear discharge and hearing loss.

Citation:
Brennan-Jones CG, Head K, Chong LY, Daw J, Veselinović T, Schilder AGM, Bhutta MF. Topical antibiotics for chronic suppurative otitis media. Cochrane Database Syst Rev. 2025;2025(6).

Keywords:
Topical; anti-bacterial agents; administration; dosage; adverse effects; therapeutic use; chronic disease; otitis media; suppurative; randomized controlled trials

Abstract:
Chronic suppurative otitis media (CSOM), sometimes referred to as chronic otitis media, is a chronic inflammation and often polymicrobial infection (involving more than one micro-organism) of the middle ear and mastoid cavity, characterised by ear discharge (otorrhoea) through a perforated tympanic membrane. The predominant symptoms are ear discharge and hearing loss.