Jet versus vibrating mesh nebulizer for tobramycin aerosol in spontaneously breathing children with tracheostomies: A simulation study

Tracheostomy tubes act as foreign bodies, predisposing the surrounding airway to respiratory infections. Initial treatment for infections is topical - nebulized tobramycin - although guidelines for standardized treatment are lacking.

Citation:
Anderson NVE, Ditcham WGF, Clements BS, von Ungern-Sternberg BS. Jet versus vibrating mesh nebulizer for tobramycin aerosol in spontaneously breathing children with tracheostomies: A simulation study. Anaesth Crit Care Pain Med. 2025;44(1).

Keywords:
Aerosol delivery; In vitro model; Inhaled antibiotic; Nebulized antibiotic; Pediatrics; Tobramycin

Abstract:
Tracheostomy tubes act as foreign bodies, predisposing the surrounding airway to respiratory infections. Initial treatment for infections is topical - nebulized tobramycin - although guidelines for standardized treatment are lacking.